Dementia with Lewy Bodies

Dementia with Lewy Bodies (DLB) is a progressive type of dementia that affects over 1 million people in the United States.  DLB is characterized by buildup of abnormal protein clusters (known as Lewy Bodies) in the brain. People with DLB have fluctuations in cognition, particularly in alertness and attention. Many people with DLB can have visual hallucinations and REM sleep disturbance disorders.

Currently, there are no approved treatments for Lewy Body dementia in the United States or Europe.

About the AscenD-LB Trial:

The AscenD-LB study will test an investigational medication to see if it might improve attention, memory, and cognitive function in patients who have Dementia with Lewy Bodies.

Who Is Eligible to Participate? 

Patients may qualify for this study if they: 

  • Are age 55 or older
  • Have probable DLB*
  • Have no neurological condition contributing to cognitive impairment beyond those caused by DLB 
  • Are currently take a cholinesterase inhibitor therapy*
  • Have a study partner who can provide information about the patient throughout the study.This person will attend all study visits with the study participant.

*if you are unsure of a diagnosis or the type of medication you are taking, feel free to contact the study team we may be able to help identify the type of medication and the doctors at the Memory Health Center may be able to provide a no cost pre-study evaluation. 

To see if you may qualify, please call us at the number listed above in the top right corner of the page, or fill out the form to the right and we will contact you.

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